Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
Growth Hormone-Releasing Peptide (GHRP)
Weekly Protocol Guide
Hexarelin Protocol Guide
Hexarelin is the strongest of the GHRPs, producing the most potent GH release per dose. It acts on the ghrelin receptor (GHS-R1a) to stimulate pituitary GH secretion. Note: Hexarelin can raise cortisol and prolactin levels, particularly at higher doses. Desensitization may occur with prolonged continuous use.
Protocol Overview
- Compound
- Hexarelin (Hexarelin Acetate)
- Category
- Growth Hormone-Releasing Peptide (GHRP)
- Vial Size
- 5mg (5,000mcg)
- Reconstitution
- 2mL bacteriostatic water (2.5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- 2-3x daily, 5 days/week
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 2.5mg/mL. Always use sterile techniques.
Materials Needed
- 5mg Hexarelin 5mg vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the Hexarelin 5mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Weekly Dosing Schedule
Standard Protocol (200mcg 3x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Monday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Tuesday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Wednesday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Thursday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Friday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Saturday | Rest day | ||
| Sunday | Rest day | ||
Weekly Total: 120 units (3,000mcg) • Vial Duration: ~12 days
Moderate Protocol (200mcg 2x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Mon-Fri | 16 | 400mcg (2x 200mcg) | AM fasted, before bed |
| Sat-Sun | Rest days | ||
Weekly Total: 80 units (2,000mcg) • Vial Duration: ~18 days
Beginner Protocol (100mcg 1x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Mon-Fri | 4 | 100mcg | Before bed |
| Sat-Sun | Rest days | ||
Weekly Total: 20 units (500mcg) • Vial Duration: ~70 days
Cycling: 4-8 weeks on, 2-4 weeks off to prevent receptor desensitization. Hexarelin is especially prone to desensitization with continuous use.
Quick Dosing Reference
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 2 | 50 | 0.05mg |
| 4 | 100 | 0.1mg |
| 8 | 200 | 0.2mg |
| 12 | 300 | 0.3mg |
| 20 | 500 | 0.5mg |
Administration Guidelines
- Administer subcutaneously on an empty stomach (2+ hours after eating) - optimal times: AM fasted, post-workout, before bed
- Strongest GHRP - start at 100mcg 1x/day and titrate up to 200mcg 2-3x/day as tolerated
- Can raise cortisol and prolactin levels at higher doses - monitor accordingly
- Rotate injection sites between abdomen, thigh, and upper arm
- Consider cycling 4-8 weeks on, 2-4 weeks off to avoid desensitization
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |