Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
Growth Hormone-Releasing Peptide (GHRP)
Weekly Protocol Guide
Hexarelin Protocol Guide
⚠ No validated human dose. This compound is not FDA-approved and has no peer-reviewed human dose-finding trials. The figures below are research conventions extrapolated from preclinical (animal/in‑vitro) and community sources — not validated clinical dosing. Treat them as study references only. Research use only; not medical advice.
Hexarelin is the strongest of the GHRPs, producing the most potent GH release per dose. It acts on the ghrelin receptor (GHS-R1a) to stimulate pituitary GH secretion. Note: Hexarelin can raise cortisol and prolactin levels, particularly at higher doses. Desensitization may occur with prolonged continuous use.
Protocol Overview
- Compound
- Hexarelin (Hexarelin Acetate)
- Category
- Growth Hormone-Releasing Peptide (GHRP)
- Vial Size
- 5mg (5,000mcg)
- Reconstitution
- 2mL bacteriostatic water (2.5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- 2-3x daily, 5 days/week
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 2.5mg/mL. Always use sterile techniques.
Materials Needed
- 5mg Hexarelin 5mg vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the Hexarelin 5mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Weekly Dosing Reference · research convention, not a validated dose
Standard Protocol (200mcg 3x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Monday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Tuesday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Wednesday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Thursday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Friday | 24 | 600mcg (3x 200mcg) | AM fasted, post-workout, before bed |
| Saturday | Rest day | ||
| Sunday | Rest day | ||
Weekly Total: 120 units (3,000mcg) • Vial Duration: ~12 days
Moderate Protocol (200mcg 2x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Mon-Fri | 16 | 400mcg (2x 200mcg) | AM fasted, before bed |
| Sat-Sun | Rest days | ||
Weekly Total: 80 units (2,000mcg) • Vial Duration: ~18 days
Beginner Protocol (100mcg 1x/day, 5 days/week)
| Day | Units | Dose | Timing |
|---|---|---|---|
| Mon-Fri | 4 | 100mcg | Before bed |
| Sat-Sun | Rest days | ||
Weekly Total: 20 units (500mcg) • Vial Duration: ~70 days
Cycling: 4-8 weeks on, 2-4 weeks off to prevent receptor desensitization. Hexarelin is especially prone to desensitization with continuous use.
Quick Dosing Reference · research convention, not a validated dose
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 2 | 50 | 0.05mg |
| 4 | 100 | 0.1mg |
| 8 | 200 | 0.2mg |
| 12 | 300 | 0.3mg |
| 20 | 500 | 0.5mg |
Administration Guidelines
- Administer subcutaneously on an empty stomach (2+ hours after eating) - optimal times: AM fasted, post-workout, before bed
- Strongest GHRP - start at 100mcg 1x/day and titrate up to 200mcg 2-3x/day as tolerated
- Can raise cortisol and prolactin levels at higher doses - monitor accordingly
- Rotate injection sites between abdomen, thigh, and upper arm
- Consider cycling 4-8 weeks on, 2-4 weeks off to avoid desensitization
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |