Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.

GLP-1 Receptor Agonist Weekly Protocol Guide

Liraglutide Protocol Guide

✓ Verified dosing (fact-checked against FDA labels / published trials): Subcutaneous injection, ONCE DAILY (not weekly). Weight management (Saxenda): titrate 0.6 mg/day (wk1) -> 1.2 (wk2) -> 1.8 (wk3) -> 2.4 (wk4) -> 3.0 mg/day maintenance. Type 2 diabetes (Victoza): 0.6 mg/day x1 week -> 1.2 mg/day -> up to 1.8 mg/day max. 0.6 mg is only the initial titration dose. This supersedes any conflicting figures shown elsewhere on this page; confirm with a licensed provider.

Liraglutide is a GLP-1 receptor agonist with 97% homology to native GLP-1. It is studied for weight management and metabolic research. It reduces appetite and caloric intake via central satiety pathways and delayed gastric emptying.

Protocol Overview

Compound: Liraglutide (Saxenda - Weight Loss Research Peptide)
Category: GLP-1 Receptor Agonist
Vial Size: 6mg (6,000mcg)
Reconstitution: 2mL bacteriostatic water (3mg/mL)
Route: Subcutaneous injection
Frequency: 7 days/week

Reconstitution Instructions

Using 2mL of bacteriostatic water results in a concentration of 3mg/mL. Start at 0.6mg and titrate up weekly. Always use sterile techniques.

Materials Needed

6mg Liraglutide 6mg vial (lyophilized powder)
2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
Sterile syringe and needle (18-22 gauge for drawing)
Alcohol swabs
Clean workspace

Step-by-Step Process

Preparation: Allow the Liraglutide 6mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.

Administration Guidelines

Administer subcutaneously once daily at approximately the same time each day
Start at 0.6mg daily for one week then titrate up by 0.6mg each week to target of 3.0mg
Rotate injection sites between abdomen, thigh, and upper arm
Common initial side effects include nausea - titrate slowly to minimize
Store reconstituted peptide refrigerated at 36-46F (2-8C)
Use reconstituted solution within 30 days
Never freeze reconstituted peptides
Document administration times and observations

Storage Requirements

State	Storage Conditions
Lyophilized (powder)	Room temperature or refrigerated, protect from light
Reconstituted	Refrigerated 36-46F (2-8C), use within 30 days

Related Tools & Resources

Dosing Calculator Reconstitution Calc Bloodwork Planner Stack Checker

Frequently Asked Questions

What is the standard Liraglutide dosing protocol?▼

See the fact-checked Verified Dosing shown at the top of this page (verified against the FDA label / published trials); always confirm with a licensed provider.

How do you reconstitute Liraglutide?▼

Using 2mL of bacteriostatic water results in a concentration of 3mg/mL. Start at 0.6mg and titrate up weekly. Always use sterile techniques.

What are the storage requirements for Liraglutide?▼

Lyophilized (powder): Room temperature or refrigerated, protect from light. Reconstituted: Refrigerated 36-46F (2-8C), use within 30 days.