Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
Research Peptide
Weekly Protocol Guide
PT-141 Protocol Guide
PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist studied for sexual function signaling pathways via MC3R and MC4R in the central nervous system.
Protocol Overview
- Compound
- PT-141 (Bremelanotide (Melanocortin Receptor Agonist))
- Category
- Research Peptide
- Vial Size
- 10mg (10,000mcg)
- Reconstitution
- 2mL bacteriostatic water (5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- As needed (max 8x/month)
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 5mg/mL. Always use sterile techniques.
Materials Needed
- 10mg PT-141 vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the PT-141 vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Dosing Schedule (As-Needed Protocol)
PT-141 is used on an as-needed basis, NOT daily. Administer 45–60 minutes before desired effect. Do not exceed 1 dose per 24 hours or 8 doses per month.
| Protocol | Dose | Units (at 5mg/mL) | Timing |
|---|---|---|---|
| Starting dose | 1mg | 20 units (0.2mL) | 45–60 min before activity |
| Standard dose | 1.75mg | 35 units (0.35mL) | 45–60 min before activity |
| Max single dose | 2mg | 40 units (0.4mL) | 45–60 min before activity |
Standard dose: 1–2mg per use • Vial Duration: ~5–10 uses (10mg vial) • Max 8 doses per month
Quick Dosing Reference (at 5mg/mL)
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 10 | 500 | 0.5mg |
| 20 | 1,000 | 1mg |
| 30 | 1,500 | 1.5mg |
| 35 | 1,750 | 1.75mg |
| 40 | 2,000 | 2mg |
Administration Guidelines
- Administer subcutaneously 45-60 minutes before desired effect
- Do not use more than once in 24 hours
- Do not exceed 8 doses per month
- Rotate injection sites
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |