S-4 (Andarine) Protocol Guide
S-4 (Andarine) is one of the earlier SARMs developed, studied for fat loss and lean mass retention. Research shows a favorable effect on body composition with moderate anabolic activity. A notable research finding is dose-dependent visual side effects (yellow tint to vision, difficulty with night vision) believed to be related to binding to retinal receptors. These effects are temporary and resolve upon discontinuation. Capsule Content 25mg per capsule (25,000mcg per capsule) Route of Administration Oral (capsule)
Protocol Overview
- Compound
- S-4 (Andarine) (Oral Research Compound - Fat Loss / Lean Mass)
- Category
- Selective Androgen Receptor Modulator
- Vial Size
- 25mg capsules
- Reconstitution
- N/A — oral compound
- Route
- Oral (capsule or liquid)
- Frequency
- 7 days/week
Administration Instructions
This is an oral compound. No reconstitution is required.
How to Take
- Swallow capsule with a full glass of water
- Take at the same time each day for consistent blood levels
- Can be taken with or without food
- Store in original container at room temperature, away from moisture and light
- Document administration times in research log
Weekly Dosing Reference · research convention, not a validated dose
| Day | Units | Dose | Timing |
|---|---|---|---|
| Monday | 1 cap | 25mg | Morning |
| Tuesday | 1 cap | 25mg | Morning |
| Wednesday | 1 cap | 25mg | Morning |
| Thursday | 1 cap | 25mg | Morning |
| Friday | 1 cap | 25mg | Morning |
| Saturday | 1 cap | 25mg | Morning |
| Sunday | 1 cap | 25mg | Morning |
Weekly Total: 7 capsules (175mg) • Cycle Duration: 8 weeks on, 4 weeks off
Quick Dosing Reference · research convention, not a validated dose
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 1 cap | 25mg | Standard starting dose |
| 2 caps | 50mg | Advanced research dose |
Administration Guidelines
- Take orally with water in the morning
- Cycle length: 8 weeks on followed by 4 weeks off
- Dose range: 25-50mg per day
- 5 days on / 2 days off protocol may reduce vision side effects
- Monitor for vision changes (yellow tint or night vision difficulty)
- PCT (Post Cycle Therapy) recommended after each cycle
- Liver support supplement recommended during cycle
- Reduce dose or discontinue if vision side effects occur
- Store capsules at room temperature in a cool dry place
- Keep away from direct sunlight and moisture
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Capsules (sealed) | Room temperature, cool dry place, protect from light |
| Capsules (opened) | Keep tightly sealed, away from moisture and heat |
Related Tools & Resources
Frequently Asked Questions
There is no validated human dose for this compound; the following is a commonly cited research convention, not a validated protocol. The standard S-4 (Andarine) research protocol uses 25mg administered morning on protocol days. Weekly Total: 7 capsules (175mg) • Cycle Duration: 8 weeks on, 4 weeks off
S-4 (Andarine) is an oral compound supplied as capsules. No reconstitution is required. Swallow the capsule with water at the same time each day.
Store capsules at room temperature in a cool, dry place. Keep tightly sealed, away from moisture and direct light.