Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
GHRH Analog
Weekly Protocol Guide
Sermorelin Protocol Guide
✓ Verified dosing (fact-checked against FDA labels / published trials): FDA-approved (Geref Pediatric, GHD): 30 mcg/kg/day (0.03 mg/kg) subcutaneously ONCE DAILY at bedtime, every day. FDA diagnostic (Geref): 1 mcg/kg IV single dose. Off-label adult wellness (compounded, not FDA-approved): commonly 100-500 mcg (typically 200-300 mcg) subcutaneously once daily at bedtime, EVERY day — not 5 days/week. Route is correct (SubQ);… This supersedes any conflicting figures shown elsewhere on this page; confirm with a licensed provider.
Sermorelin is a synthetic analog of the first 29 amino acids of naturally occurring GHRH. It stimulates the pituitary gland to produce and release growth hormone in a natural pulsatile pattern.
Protocol Overview
- Compound
- Sermorelin (Growth Hormone-Releasing Hormone (1-29))
- Category
- GHRH Analog
- Vial Size
- 10mg (10,000mcg)
- Reconstitution
- 2mL bacteriostatic water (5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- 5 days/week
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 5mg/mL. Always use sterile techniques.
Materials Needed
- 10mg Sermorelin 10mg vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the Sermorelin 10mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Administration Guidelines
- Administer subcutaneously before bed on an empty stomach (2+ hours after eating)
- Rotate injection sites between abdomen, thigh, and upper arm
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |