Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
GHRH Analog
Weekly Protocol Guide
Tesamorelin Protocol Guide
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce and release growth hormone naturally.
Protocol Overview
- Compound
- Tesamorelin (Growth Hormone-Releasing Hormone Analog)
- Category
- GHRH Analog
- Vial Size
- 5mg (5,000mcg)
- Reconstitution
- 2mL bacteriostatic water (2.5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- Once daily (or 5 days/week)
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 2.5mg/mL. Always use sterile techniques.
Materials Needed
- 5mg Tesamorelin 5mg vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the Tesamorelin 5mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Daily Dosing Schedule
Tesamorelin (FDA-approved as Egrifta) is administered at 2mg (2,000mcg) once daily subcutaneously. The standard dose does not require titration.
| Day | Units | Dose | Timing |
|---|---|---|---|
| Daily | 80 | 2mg (2,000mcg) | Morning, before breakfast |
Standard dose: 2mg once daily • Vial Duration: ~2.5 doses per 5mg vial • Inject subcutaneously in abdomen
Quick Dosing Reference (at 2.5mg/mL)
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 20 | 500 | 0.5mg |
| 40 | 1,000 | 1mg |
| 60 | 1,500 | 1.5mg |
| 80 | 2,000 | 2mg |
| 100 | 2,500 | 2.5mg |
Administration Guidelines
- Administer subcutaneously in the morning on an empty stomach
- Rotate injection sites between abdomen, thigh, and upper arm
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |