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Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
Research Compound Weekly Protocol Guide

Tesofensine Protocol Guide

✓ Verified dosing (fact-checked against FDA labels / published trials): Oral, once-daily. Clinically studied doses: 0.25-1.0 mg (250-1000 mcg) PO once daily; 0.5 mg (500 mcg) once daily is the expected recommended dose (~10% weight loss at 24 weeks). Taken continuously every day (not cyclically), not injected. Not FDA-approved. This supersedes any conflicting figures shown elsewhere on this page; confirm with a licensed provider.

Tesofensine is a triple monoamine reuptake inhibitor blocking reuptake of norepinephrine, dopamine, and serotonin, studied for appetite suppression and metabolic rate effects.

Protocol Overview

Compound
Tesofensine (Triple Monoamine Reuptake Inhibitor)
Category
Research Compound
Vial Size
500mcg capsule (500mcg)
Reconstitution
N/A (oral capsule)
Route
Oral
Frequency
7 days/week

Administration

Take orally with water. No reconstitution or injection required.

  • Take with or without food (unless otherwise noted)
  • Store at room temperature in a cool, dry place
  • Follow the dosing schedule consistently

Administration Guidelines

  • Take orally with water in the morning
  • Can be taken with or without food
  • Do not exceed recommended dose
  • Store at room temperature in a cool dry place
  • Keep away from direct sunlight and moisture
  • Document administration times and observations

Storage Requirements

StateStorage Conditions
Sealed containerRoom temperature or refrigerated, protect from light
Opened containerRoom temperature, keep sealed, use within 90 days
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⚠ Before any use: human safety data is limited or absent for many of these compounds. Consult a licensed healthcare provider first — especially if you are pregnant or nursing, have a medical condition, or take other medications.